X. Y. Jia, Z. H. Tian, L. Shao, X. D. Qu, Q. F. Zhao, J. Tang, G. L. Tang and W. Liu, Chem. Biol., 2006, 13, 575–585 CrossRef CAS PubMed.

Match Game / Bob Keeshan / Gumby / The Flip Wilson Show / Glen Campbell Goodtime Hour / The Bobby Darin Show / The Richard Pryor Show / George Burns / Celebrity Commercials E. Q. King, C. N. Lewis, H. Welch, E. A. Clark, J. B. Johnson, J. B. Lyons, R. B. Scott and P. B. Cornely, J. Am. Med. Assoc., 1950, 143, 1–4 CrossRef CAS PubMed.The brilliant but mentally unstable inventor of a device capable of remotely overloading and destroying any active electrical or electronic circuit is attempting to destroy Probe Control. a projecting, pipelike device on a receiving aircraft used to make connection with and receive fuel from a tanker aircraft during refueling in flight. The series centers on World Securities Corporation, a high-tech international private investigation company that employs field operatives, the elite of whom, probes, are aided by implanted audio receivers and scanners, tiny video camera/ telemetry units which can be attached to tie clips or other jewelry. A common method is to wear the scanner on a ring, enabling it to be discreetly aimed. By improving our understanding of targets and pathways, chemical probes can have a major impact in enabling and accelerating the discovery and development of new pharmaceuticals. For example, JQ1 and I-BET, BET inhibitor probes first published in 2010, have been linked to acute myeloid leukemia (AML) and multiple myeloma (MM) and have already led to more than 30 clinical trials. 1 Biological properties include a known MoA, high in vitro potency, high selectivity, and demonstrated on-target effects in cells.

O. Yushchuk, M. Kharel, I. Ostash and B. Ostash, Appl. Microbiol. Biotechnol., 2019, 103, 1659–1665 CrossRef CAS PubMed. Postcodes for Highlands and Islands of Scotland, N Ireland, Isle of Man & Isles of Scilly, Channel Islands and Isle of Wight are: FK17-99, G83, KW1-14, IV, HS, KA27-28, PA20-49, PA60-78, PH15-26, PH30-44, PH49-50, ZE, AB51 W. J. Zhang, B. D. Ames, S. C. Tsai and Y. Tang, Appl. Environ. Microbiol., 2006, 72, 2573–2580 CrossRef CAS PubMed. M. Hatsu, T. Sasaki, H. Watabe, S. Miyadoh, M. Nagasawa, T. Shomura, M. Sezaki, S. Inouye and S. Kondo, J. Antibiot., 1992, 45, 320–324 CrossRef CAS PubMed.

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Albert Popwell as Albert Griffin, linguist and code-breaker; former chief translator at the United Nations This usage of chemical probes, while consistent with recent drug discovery terminology, should not be confused with probes used in genomics research—DNA or RNA sequences labeled with fluorescent or radioactive tags that can be used to search for their complementary sequences in a sample genome.

J. D. Rudolf, X. Yan and B. Shen, J. Ind. Microbiol. Biotechnol., 2016, 43, 261–276 CrossRef CAS PubMed. Fig. 2 HPLC analysis of HaiO2-catalyzed reactions. (i) authentic 2, (ii) authentic 3, (iii) authentic 4, (iv) HaiO2 incubated with 3 and NADPH, (v) boiled HaiO2 incubated with 3 and NADPH, (vi) HaiO2 incubated with 2 and NADPH, and (vii) boiled HaiO2 incubated with 2 and NADPH. Search was featured in the November 1972 edition of TV Guide, with an illustration of the three actors playing the show's "probes" on the cover. [4] Probe field agents [ edit ] M. Thaker, P. Spanogiannopoulos and G. D. Wright, Cell. Mol. Life Sci., 2010, 67, 419–431 CrossRef CAS PubMed. Soupy Sales / The Carpenters / Route 66 / Bozo / The Carpenters Christmas Specials / Local Kid Shows / Death of TV's Superman / Wonderama / Sesame Street / Bob Hope Specials / Little Rascals / 1980's Retro Gay T-Shirts / 1980's TV Wrestling / Fess Parker / Howdy Doody /Z. Feng, D. Kallifidas and S. F. Brady, Proc. Natl. Acad. Sci. U. S. A., 2011, 108, 12629–12634 CrossRef CAS PubMed. All TaqMan Assays are designed using our industry-leading bioinformatics design process and meet all of our high quality-control specifications. For any given target, we compare all assays for that target and select a Best Coverage assay for standard gene expression experiments that detects the maximum number of transcripts for the gene of interest. We also evaluate the assays based on the design criteria below with the recommended assay best meeting the criteria. The apparent suicide of an alleged embezzler, whose widow hires Probe to investigate, leads Bianco to infiltrate a most unusual travel agency: a front for a criminal counterpart to the Witness Protection Program. Diana Muldaur and Sebastian Cabot are prominent guest stars.