Ghedira K. Goetz P. Jeune R. L. Alchemilla vulgaris. Phytothérapie. 2012:263–266. doi: 10.1007/s10298-012-0719-9. [ CrossRef] [ Google Scholar] L. Campbell, J. Gee, K. M. Taylor, R. I. Nicholson, M. Gumbleton and Á. Ráháeáerk, Growth of hormone-dependent MCF-7 breast cancer cells is promoted by constitutive caveolin-1 whose expression is lost in an EGF-R-mediated manner during development of tamoxifen resistance, Breast Cancer Res. Treat., 2010, 575–591 Search PubMed. Warm regions that experience high humidity may have issues with fungal problems, particularly if the crown is kept damp. Providing adequate air circulation and allowing the soil to slightly dry out some should help remedy this.

Adamczyk B, Simon J, Kitunen V, Adamczyk S, Smolander A. Tannins and their complex interaction with different organic nitrogen compounds and enzymes: old paradigms versus recent advances. ChemistryOpen. 2017;6(5):610-614. View abstract. Also known as lady’s mantle, these popularclump-forming perennialshave a gentle, under-stated charm, with attractive leaves and frothy summer flowers. The velvety leaves are water-resistant and after rain are left bejewelled with round droplets.Alchemilla pratensis var. acutangula (Buser) Schinz & R.Keller in Fl. Schweiz, ed. 2, 2: 118 (1905)

L. Schröder, P. Marahrens, J. G. Koch, H. Heidegger, T. Vilsmeier and T. Phan-brehm, et al., Effects of green tea, matcha tea and their components epigallocatechin gallate and quercetin on MCF-7 and MDA-MB-231 breast carcinoma cells, Oncol. Rep., 2019, 2(9), 387–396 Search PubMed. When it comes to menopause, lady’s mantle has a reputation among herbalists for being an effective herbal remedy for symptoms like hot flashes and anxiety. ( 3)

What is Lady's Mantle?

P. Prieto, M. Pineda and M. Aguilar, Spectrophotometric Quantitation of Antioxidant Capacity through the Formation of a Phosphomolybdenum Complex: Specific Application to the Determination of Vitamin E1, Anal. Biochem., 1999, 341, 337–341 CrossRef PubMed. M. Hashemzaei, A. D. Far, A. Yari, R. E. Heravi, K. Tabrizian and S. M. Taghdisi, et al., Anticancer and apoptosis – inducing effects of quercetin in vitro and in vivo, Oncol. Rep., 2017, 819–828 CrossRef CAS PubMed. Even though this ingredient is considered safe in high concentrations, it’s often used in very low amounts.

Alchemilla vulgaris agg. (Lady's mantle) from central Balkan: antioxidant, anticancer and enzyme inhibition properties Lady’s mantle is easy to grow. Typically, the plant grows well in regions with cool summers and moist, fertile soil and is hardy in USDA plant hardiness zones 3-7. While it can tolerate full sun, lady’s mantle performs better in shade when grown in warmer regions. S. Chakrabarty, A. Ganguli, A. Das, D. Nag and G. Chakrabarti, Chemico-Biological Interactions Epigallocatechin-3-gallate shows anti-proliferative activity in HeLa cells targeting tubulin-microtubule equilibrium, Chem.-Biol. Interact., 2015, 242, 380–389, DOI: 10.1016/j.cbi.2015.11.004.A. I. Martinez-Gonzalez, Á. G. Díaz-Sánchez, A. de la Rosa, I. Bustos-Jaimes and E. Alvarez-Parrilla, Inhibition of α -amylase by flavonoids: Structure–activity relationship (SAR), Spectrochim. Acta, Part A, 2019, 206, 437–447 CrossRef CAS PubMed.

Forêt, Rosalee de La. "Plants in France: Lady's Mantle." Methow Valley Herbs. N.p., 01 Jan. 1970. Web. 25 Feb. 2017. http://www.methowvalleyherbs.com/2012/08/plants-in-france-ladys-mantle.html Alchemillas are very adaptable andgrow well in sun or partial shade, in most soil types, including clay J. Zivkovic, C. Nada and M. Terě, Ethnobotanical study on traditional use of medicinal plants in South-Western Serbia, Zlatibor District, 2013 Search PubMed.Alchemilla vulgaris subsp. acutiloba (Opiz) Dostál in Klíč Úplné Kvĕt. ČSR: 364 (1954), nom. illeg. Some other specific conditions where this action could be useful could be in cases endometriosis or fibroids with excessive bleeding because Lady’s Mantle tones and dries the womb and pelvic area. In her book, Herbal Remedies for Women, Amanda McQuade Crawford (1997) states that astringent herbs with an affinity for the uterus like Lady’s Mantle are primary herbs to think of in cases of cervical dysplasia.